Liver Dysfunction

 LIVER DYSFUNCTION 

Dysfunction of the liver may be divided into 4 categories that may coexist:

 

•         Hepatic failure occurs in the setting of hepatic necrosis secondary to acute liver failure, chronic liver disease, and hepatocyte dysfunction.

 

•         Portal hypertension occurs in the setting of cirrhosis or increased portal venous blood flow.

 

•         Cholestasis occurs in the setting of impaired bile flow due to hepatocyte dysfunction or biliary obstruction.

 

•         Cirrhosis occurs in the setting of hepatocyte injury and is usually an irrevers-ible nodular regeneration that is end stage.

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